Description_x000D_ Amino Acid Sequence_x000D_ H-Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg-OH_x000D_ General description_x000D_ Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes._x000D_ The peptide is a major MHC class II-restricted T-cell epitope of Ovalbumin which is used for studies of immunological allergic responses such as asthma, food allergy and more.._x000D_ Application_x000D_ Ovalbumin (323-339) (chicken, Japanese quail) has been used to induce allergic asthma in mice._x000D_ Biochem/physiol Actions_x000D_ Ovalbumin (OVA) peptide 323-339 mediates 25–35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation._x000D_ With the help of two functionally distinct registers ovalbumin (323-339) peptide can bind to histocompatibility complex class II I-A(d) protein._x000D_ Physical form_x000D_ Lyophilized from 0.1% aqueous TFA_x000D_ Other Notes_x000D_ Lyophilized from 0.1% TFA in H2O