PROGESTERONE, CELL CULTURE TESTED

Description_x000D_ General description_x000D_ Progesterone is a steroid hormone secreted by the ovaries._x000D_ Application_x000D_ Progesterone has been used:_x000D_ • as a growth-promoting hormone in basal medium for bovine mammary epithelial cell culture_x000D_ • to test its neuroprotective abilities in a well-characterized lateral cortical contusion injury (CCI) model_x000D_ • as an endocytosis inhibitor to study its effect on Coxsackievirus A9 infection on A549 cells_x000D_ Packaging_x000D_ 1, 5, 25 g in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer._x000D_ Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility._x000D_ Other Notes_x000D_ Steroid hormone produced by the corpus luteum._x000D_ Physical form_x000D_ powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw_x000D_ Reconstitution_x000D_ To prepare 20μg/ml stock solution, add 1ml absolute ethanol per mg progesterone, gently swirl to dissolve, add 49ml sterile medium per ml ethanol.