RETINAL

Description_x000D_ General description_x000D_ All trans-Retinal is one of the major derivatives of vitamin A group. A variety of food serves as a source of vitamin A. It is predominant in liver and among the brightly colored vegetables._x000D_ Application_x000D_ All trans-Retinal has been used:_x000D_ • in optogenetic experiments_x000D_ • in electrophysiological experiment_x000D_ • to study the effect of AKR1B10 (aldo-keto reductase (AKR) superfamily member) on the conversion of retinal to retinol in the airway epithelium_x000D_ • in decidual transformation of human endometrial stromal cells_x000D_ Packaging_x000D_ 1 g in ampule_x000D_ 25, 100, 500 mg in ampule_x000D_ Biochem/physiol Actions_x000D_ All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells. Retinal isomers are also chromophores that bind to opsins, a family of G-protein-linked transmembrane proteins, to form photosensitive receptors in visual and nonvisual systems. All-trans retinal is a potent photosensitizer._x000D_ Packaging_x000D_ Sealed ampule._x000D_ Other Notes_x000D_ Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. R2500.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.