SAPONIN FROM QUILLAJA BARK

Description_x000D_ General description_x000D_ Saponins are natural steroidal glycoside (terpenes)._x000D_ Application_x000D_ Saponin from Quillaja bark has been used:_x000D_ • to stain CD4+ and CD8+ T-cells_x000D_ • to lyse trophozoite-infected red blood cells_x000D_ • in immunohistochemical staining_x000D_ Packaging_x000D_ 25, 100 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Hence it is used as vaccine adjuvants. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects._x000D_ Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro._x000D_ Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.