Description_x000D_ General description_x000D_ Chemical structure: aminoglycoside_x000D_ Biochem/physiol Actions_x000D_ Mode of Action: Spectinomycin acts by inhibiting protein synthesis and elongation by binding to the bacterial 30S ribosomal subunit and interfering with peptidyl tRNA translocation._x000D_ Mode of Resistance: A mutation in rpsE, the gene for ribosomal protein S5, prevents the binding of spectinomycin. Resistance is also conferred by the aminoglycoside-3'-adenyltransferase gene (aadA)._x000D_ Antimicrobial spectrum: Spectinomycin acts against gram-negative and gram-positive bacteria._x000D_ Packaging_x000D_ 100MG_x000D_ Caution_x000D_ Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods._x000D_ Preparation Note_x000D_ Stock solutions should be prepared at 10 mg/mL in water and filter sterilized._x000D_ Other Notes_x000D_ Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.