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Description_x000D_
Packaging_x000D_
5, 25 mg in glass bottle_x000D_
Biochem/physiol Actions_x000D_
TVP1022, the S-isomer of rasagiline, an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. TVP1022, a neuroprotective and cytoprotective molecule, is also cardioprotective in rat models. Its activity is believed to involve stabilization of mitochondrial membrane potential, induction of Bcl-2 and activation of the PKC signalling pathway, enhancing the phosphorylation of protein kinase C and glycogen synthase kinase-3β.
- Related Categories Antioxidants and Cytoprotectants, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Kinase/Phosphatase Biology, Nitric Oxide and Cell Stress, Protein Kinase C (PKC), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology, TMore... Quality Level
