Description_x000D_ General description_x000D_ WIN 55,212-2 is a member of the aminoalkylindole class of compounds._x000D_ Application_x000D_ (R)-(+)-WIN 55,212-2 mesylate salt has been used as a high affinity cannabinoid agonist for intraperitoneal injection into rats to induce behavioural sensitization. It has also been used as a synthetic cannabinoid drug and cannabinoid receptor 1 (CNR1) agonist to treat Becn2+/− mice and wild-type (WT) littermate to analyze the levels of CNR1 in the brain._x000D_ Packaging_x000D_ 100 mg in glass bottle_x000D_ 25 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ It is known to decrease the lipopolysaccharide mediated release of tumor necrosis factor- α and interleukin-1 in mice._x000D_ Features and Benefits_x000D_ This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ Legal Information_x000D_ Sold with the permission of Sterling-Winthrop, Inc.